Cancer Genome and Tumor Microenvironment

Oncogenes and tumor suppressor genes had been traditionally studied in the context of cell proliferation, differentiation, senescence, and survival, four relatively cell-autonomous processes. Consequently, in the late ’80s-early ’90s, neoplastic growth was described largely as an imbalance between net cell accumulation and loss, brought about through mutations in cancer genes.

Books about The Tumor Microenvironment: Recent Advances and Novel Therapeutic Approaches

Books about Exploring the breast tumor microenvironment: Association to metastasis, novel risk factors and novel treatments and immunotherapies

Books about Manipulating the Immunological Tumor Microenvironment

Cancer is a complex disease driven by genetic variation(1-3). Two main types of genetic variation include germline variation, which is inherited, and somatic variation, which is acquired through environmental exposures and endogenous processes, such as DNA replication. Both types of genetic variation have been critical for precision medicine, tailored to