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Opioid Analgesics

Release on 2013-06-292013-06-29 by A.F. Casy
Opioid Analgesics

Author: A.F. Casy

Publisher: Springer Science & Business Media

ISBN: 9781489905857

Category: Medical

Page: 518

View: 357

The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal gesics particularly relevant and timely. After an introductory chapter the additional 12 chapters begin logically with morphine and congeners (4- epoxymorphinans) and end with opioid receptors. All principal chemical types of centrally acting analgesics (including endogenous opioid-like substances) and their antagonists as well as the mixed agonist-antagonists are treated thoroughly, although not always (and for good reason) in historical (chrono logical) order. A chapter on miscellaneous types (atypical structures for the most part) includes the benzimidazoles (etonitazene), aminotetralins (dezocine), tetrahydroisoquinolines (methopholine), and so on. Important aspects and correlations of chemistry, pharmacology, and biochemistry are discussed in depth. Literature citations are numerous. For educators, practicing laboratory scientists, and physicians, this scholarly review by two authors well of opioid analgesics versed in the chemistry, pharmacology, and biochemistry will be informative, stimulating, and thought-provoking. Everette L. May Medical College of Virginia Richmond, VA 23298 v Preface The history of opium predates the written word, although knowledge of its constituents dates back less than 200 years. Over the centuries its popularity for the relief of pain has waxed and waned, until today the opiates are widely recognized as excellent analgesics but with disadvantages that have impaired their use seriously. There is a clear need for a potent analgesic with minimal effects on the respiratory centers and gastrointestinal tract and preferably devoid of dependence liability.
Medical
Opioid Analgesics
Language: en
Pages: 518

Opioid Analgesics

Authors: A.F. Casy, R.T. Parfitt
Categories: Medical
Type: BOOK - Published: 2013-06-29 - Publisher: Springer Science & Business Media

The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal gesics particularly relevant and timely. After an introductory chapter the additional 12 chapters begin logically with morphine and congeners (4- epoxymorphinans) and end with opioid receptors. All principal
Increase in Fatal Poisonings Involving Opioid Analgesics in the United States, 1999-2006
Language: en
Pages: 8

Increase in Fatal Poisonings Involving Opioid Analgesics in the United States, 1999-2006

Authors: Margaret Warner
Categories: Accidental poisoning
Type: BOOK - Published: 2009 - Publisher:

Books about Increase in Fatal Poisonings Involving Opioid Analgesics in the United States, 1999-2006
Drug-poisoning Deaths Involving Opioid Analgesics: United States, 1999-2011
Language: en
Pages: 7

Drug-poisoning Deaths Involving Opioid Analgesics: United States, 1999-2011

Authors: Li Hui Chen, Holly Hedegaard, Margaret Warner
Categories: Drugs
Type: BOOK - Published: 2014 - Publisher:

Books about Drug-poisoning Deaths Involving Opioid Analgesics: United States, 1999-2011
Non-Opioid Analgesics in the Treatment of Acute Pain
Language: en
Pages: 21

Non-Opioid Analgesics in the Treatment of Acute Pain

Authors: Michael J Parnham
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer

Dipyrone is widely acknowledged to be an effective antipyretic analgesic with an additional intrinsic spasmolytic activity. It has stood the test of time over the last 75 years in many clinical settings throughout the world. Some 20 years ago, however, concern arose over the implications of isolat ed reports of
New Non-opioid Analgesics: Understanding Molecular Mechanisms on the Basis of Patch-clamp and chemical Studies
Language: en
Pages: 200

New Non-opioid Analgesics: Understanding Molecular Mechanisms on the Basis of Patch-clamp and chemical Studies

Authors: Boris V. Krylov, Ilia V. Rogachevskii, Tatiana N. Shelykh, Vera B. Plakhova
Categories: Science
Type: BOOK - Published: 2017-06-12 - Publisher: Bentham Science Publishers

The monograph is a summary of methods used to study pain receptors and the results obtained in some experiments designed to study the effect of non-opioid analgesics. The molecular mechanisms of nociceptive information control in primary sensory nociceptive neurons are described based on investigations of the membrane signaling cascade (opioid-like

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